Paul United via Chicago O'Hare and Denver. Worth Delta Air Lines from Atlanta, Detroit, and Minneapolis-St. Petersburg/Clearwater Beach American Eagle from Chicago O'Hare and Dallas-Ft. Airlines and cities are: Allegiant from Las Vegas, Orlando-Sanford, Phoenix-Mesa, Punta Gorda-Ft. The airport offers dozens of daily nonstop flights with international and domestic connections through many popular hub/connecting cities. Quad Cities International Airport ( IATA: MLI) is located in Moline, Illinois. The region is the largest metropolitan area on the Mississippi between Minneapolis and St. The region welcomes over 1 million visitors each year and is known for its wealth of festivals, 20+ museums, amazing bike trails, family-friendly attractions, riverboat cruises, casinos, John Deere attractions, and its micro-brewery and music scene. The Quad Cities region is located on the mighty Mississippi River, and is made up of the riverfront cities of Davenport and Bettendorf in Iowa, and Moline/East Moline and Rock Island in Illinois. The Quad Cities is a metropolitan area of five, not four, closely-entangled cities and their suburbs on either side of the Mississippi River between Iowa and Illinois.